Sickle Cell Disease in Childhood

שנת פרסום ראשונה: דצמבר 2103
שנת עדכון:
מפרסם: Pediatric Clinics of North America

KEY POINTS

  • SCD affects the entire body, beginning in very early infancy, and a multidisciplinary team is needed to care for children with SCD.
  • Some forms of SCD-related morbidity, such as overt stroke, are decreasing owing to prognostic and therapeutic advancements.
  • Primary prevention of organ injury is an important focus of current research.
  • Almost all children born with SCD in developed nations now survive to adulthood, but the transition to adult medical care is a high-risk period for death.

Pediatr Clin N Am 60 (2013) 1363–1381 http://dx.doi.org/10.1016/j.pcl.2013.09.006