שנת פרסום ראשונה: דצמבר 2013
מפרסם: Pediatric Clinics of North America
- Venous thromboembolic events (VTE), arterial thrombosis, and stroke (arterial ischemic stroke [AIS] or cerebral sinus venous thrombosis [CSVT]) are increasingly recognized in the pediatric population, and occur during 2 peak times during childhood, in the neonatal and adolescent age groups.
- In comparison with adults, acquired medical risk factors play a larger role than inherited thrombophilia in the mechanism of disease in children.
- Inherited thrombophilias have a stronger influence than VTE on pediatric stroke.
- Thrombophilia testing is indicated in adolescents with spontaneous thrombosis, and in neonates/children with non–catheter-related thrombosis and stroke.
- There are insufficient data to recommend routine thrombophilia testing in neonates/children with catheter-related thrombosis; the need for thrombophilia testing should be determined by individual institutions and on a case-by-case basis.
Pediatr Clin N Am 60 (2013) 1443–1462