KEY POINTS

• Developmental hemostasis is the evolution of the coagulation system from a fetus to an adolescent.
• The levels of procoagulant and anticoagulant protein levels differ substantially between infants and adults, and these differences affect both the ability to accurately diagnose and treat infants and children with hemostatic and thrombotic diseases.

Pediatr Clin N Am 60 (2013) 1407–1417 http://dx.doi.org/10.1016/j.pcl.2013.08.003