Dr. Sergey Postovsky, Clinical Assistant Professor, Rambam Medical Center

Epidemiology

Osteogenic sarcoma (OS) is the most common malignant bone tumor in childhood. It accounts approximately 2 per cent among all childhood cancers. The incidence rates and 95% confidence intervals of osteosarcoma for all races and both sexes are 4.0 (3.5-4.6) for the range 0-14 years and 5.0 (4.6-5.6) for the range 0-19 years per year per million persons (1). OS is tumor of predominantly seen in adolescent population and its peak is coincident with growth spurt typically seen in this age population. Since growth spurt begins in females earlier than in males, peak of OS incidence in females occurs typically 2-4 years earlier.

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