How I treat hemophagocytic lymphohistiocytosis

תאריך: 13/10/2013

Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of pathologic immune activation, occurring as either a familial disorder or a sporadic condition, in association with a variety of triggers.
This immune dysregulatory disorder is prominently associated with cytopenias and a unique combination of clinical signs and symptoms of extreme inflammation.

BLOOD, 13 OCTOBER 2011 , VOLUME 118, NUMBER 15

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How I treat autoimmune lymphoproliferative syndrome

תאריך: 24/11/2011

Autoimmune lymphoproliferative syndrome (ALPS) represents a failure of apoptotic mechanisms to maintain lymphocyte homeostasis, permitting accumulation of lymphoid mass and persistence of autoreactive cells that often manifest in childhood with chronic nonmalignant lymphadenopathy, hepatosplenomegaly, and recurringmultilineage cytopenias.

BLOOD, 24 NOVEMBER 2011 , VOLUME 118, NUMBER 22

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