Acquired thrombotic thrombocytopenic purpura (TTP) is characterized by thrombocytopenia and microangiopathic hemolytic anemia (MAHA) without an obvious
cause, and may include fever, mild renal failure, and neurologic deficits.
BLOOD, 18 JUNE 2015 x VOLUME 125, NUMBER 25
Hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP)
are 2 rare clinical entities.
Pediatr Clin N Am 60 (2013) 1513–1526, http://dx.doi.org/10.1016/j.pcl.2013.08.007
The objective of this guideline is to provide healthcare professionals with clear, up-to-date, and practical guidance on the management of TTP and related thrombotic microangiopathies, defined by thrombocytopenia, microangiopathic haemolytic anaemia (MAHA) and small vessel thrombosis.
British Journal of Haematology, 2012, 158, 323–335, doi:10.1111/j.1365-2141.2012.09167.x
Atypical haemolytic uraemic syndrome (aHUS) is associated with a poor prognosis with regard to survival at presentation, recovery of renal function and transplantation.
British Journal of Haematology, 148, 37–47, doi:10.1111/j.1365-2141.2009.07916.x
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